POSTOPERATIVE RADIOTHERAPY FOR RECTAL AND RECTOSIGMOID CANCER - THE IMPACT OF TOTAL DOSE ON LOCAL-CONTROL

被引：4

作者：

ALEMAN, BMP

LEBESQUE, JV

HART, AAM

机构：

[1] The Netherlands Cancer Institute (Antoni van Leeuwenhoek Huis), Amsterdam

来源：

RADIOTHERAPY AND ONCOLOGY | 1992年 / 25卷 / 03期

关键词：

POSTOPERATIVE RADIOTHERAPY; RECTAL CANCER; RECTOSIGMOID CANCER; DOSE-EFFECT RELATION;

D O I：

10.1016/0167-8140(92)90269-Z

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Between 1984 and 1988, 206 patients were treated with pelvic radiotherapy after macroscopically complete surgery for rectal or (recto)sigmoid cancer. Depending on an estimation of the amount of small bowel in the intended treatment volume a total dose was, in general, 45 or 50 Gy. An additional boost of 10 Gy was given to 6 patients because of microscopically involved surgical margins. For tumor stage B a statistically significant trend (p = 0.017) for higher local control with higher total dose was observed comparing patients treated with a total dose of 45 Gy or less, with more than 45 Gy but less than 50 Gy or with a total dose of 50 Gy or more. This finding illustrates the impact of total dose on local control for postoperative radiotherapy for rectal carcinoma.

引用

页码：203 / 206

页数：4

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