PROTON INVIVO SPECTROSCOPY OF PATIENTS WITH HYPERPHENYLALANINEMIA

被引：16

作者：

HAJEK, M

HEJCMANOVA, L

PRADNY, J

机构：

[1] CHARLES UNIV,SCH MED 3,DEPT PEDIAT,CS-10081 PRAGUE,CZECHOSLOVAKIA

[2] RADIOL CLIN,MR UNIT,CS-10081 PRAGUE,CZECHOSLOVAKIA

来源：

NEUROPEDIATRICS | 1993年 / 24卷 / 02期

关键词：

HYPERPHENYLALANINEMIA; H-1 MR SPECTROSCOPY; N-ACETYLASPARTATE; CHOLINE; CREATINE; MRI;

D O I：

10.1055/s-2008-1071525

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Changes in MR images and H-1 spectra of 20 patients with hyperphenylalaninaemia were compared with data of controls. Major changes in T2 MR images were found in the periventricular area (20/19). Some patients showed lesions in MR images of basal ganglia (20/7) and in the cerebellum (20/4). The results of proton MR spectroscopy show no significant difference for NAA/Cr ratios but significant ones between the ratios of NAA/Cho (p = 0.97) and Cho/Cr (p = 0.98) of controls and patients with hyperphenylalaninaemia.

引用

页码：111 / 112

页数：2

共 10 条

[1] DISTURBED MYELINATION IN PATIENTS WITH TREATED HYPERPHENYLALANINEMIA - EVALUATION WITH MAGNETIC-RESONANCE-IMAGING [J].