THE 17-BETA-ESTRADIOL DEHYDROGENASE OF PIG ENDOMETRIAL CELLS IS LOCALIZED IN SPECIALIZED VESICLES

被引：18

作者：

ADAMSKI, J

HUSEN, B

MARKS, F

JUNGBLUT, PW

机构：

[1] Max-Planck-Instit Expt Endokrinol, Postfach 61 03 09, 3000 Hannover 61

来源：

BIOCHEMICAL JOURNAL | 1993年 / 290卷

关键词：

D O I：

10.1042/bj2900777

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two monoclonal antibodies against the 17beta-oestradiol dehydrogenase of pig endometrial cells have been used in localization studies with immunogold electron microscopy. The antibodies attach both to a fraction of dehydrogenase-rich cytoplasmic vesicles isolated from homogenates and to vesicles of similar appearance in cells. The vesicles are filled with electron-dense material. Their tagging intensity indicates a high degree of specialization. Endometrial cells from mature animals contain a host of dehydrogenase vesicles, and cells from prepubertal animals only a few. Functional aspects of the novel organelle are discussed.

引用

页码：777 / 782

页数：6

共 20 条

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