SEQUENCE COMPARISON DOES NOT SUPPORT AN EVOLUTIONARY LINK BETWEEN HALOBACTERIAL RETINAL PROTEINS INCLUDING BACTERIORHODOPSIN AND EUKARYOTIC G-PROTEIN-COUPLED RECEPTORS

被引：40

作者：

SOPPA, J

机构：

[1] Max-Planck-Institut für Biochemie, 82152 Martinsried, Am Klopferspitz

来源：

FEBS LETTERS | 1994年 / 342卷 / 01期

关键词：

G-PROTEIN-COUPLED RECEPTOR; BACTERIORHODOPSIN; HALORHODOPSIN; SENSORY RHODOPSIN; RETINAL PROTEIN;

D O I：

10.1016/0014-5793(94)80573-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The structure of bacteriorhodopsin (BR) of Halobacterium halobium is known. Despite the lack of sequence similarities it is often taken as a model for eukaryotic G-protein-coupled receptors (GPCRs). Recently two hypotheses were used to support the homology of BR and GPCRs, namly evolution by exon shuffling and evolution by gene duplication. BR is a member of a family of halobacterial retinal proteins. The sequences of eight members of this family were used to test the two hypotheses. Based on sequence comparison, no indication for an evolutionary linkage between the two protein families could be found.

引用

页码：7 / 11

页数：5

共 27 条

[1] ALBERT PR, 1990, J BIOL CHEM, V265, P5825
[2] THE PROBABLE ARRANGEMENT OF THE HELICES IN G-PROTEIN-COUPLED RECEPTORS
BALDWIN, JM
[J]. EMBO JOURNAL, 1993, 12 (04) : 1693 - 1703
[3] THE HALO-OPSIN GENE .2. SEQUENCE, PRIMARY STRUCTURE OF HALORHODOPSIN AND COMPARISON WITH BACTERIORHODOPSIN
BLANCK, A
OESTERHELT, D
[J]. EMBO JOURNAL, 1987, 6 (01) : 265 - 273
[4] PRIMARY STRUCTURE OF SENSORY RHODOPSIN-I, A PROKARYOTIC PHOTORECEPTOR
BLANCK, A
OESTERHELT, D
FERRANDO, E
SCHEGK, ES
LOTTSPEICH, F
[J]. EMBO JOURNAL, 1989, 8 (13) : 3963 - 3971
[5] CHAPMAN CG, 1990, NUCLEIC ACIDS RES, V18, P2129
[6] Dayhoff MO., 1978, ATLAS PROTEIN SEQ ST, V5, P345
[7] THE BACTERIORHODOPSIN GENE
DUNN, R
MCCOY, J
SIMSEK, M
MAJUMDAR, A
CHANG, SH
RAJBHANDARY, UL
KHORANA, HG
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (11): : 6744 - 6748
[8] IDENTIFYING NONPOLAR TRANSBILAYER HELICES IN AMINO-ACID-SEQUENCES OF MEMBRANE-PROTEINS
ENGELMAN, DM
STEITZ, TA
GOLDMAN, A
[J]. ANNUAL REVIEW OF BIOPHYSICS AND BIOPHYSICAL CHEMISTRY, 1986, 15 : 321 - 353
[9] CLONING OF THE CDNA FOR THE HUMAN BETA-1-ADRENERGIC RECEPTOR
FRIELLE, T
COLLINS, S
DANIEL, KW
CARON, MG
LEFKOWITZ, RJ
KOBILKA, BK
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (22) : 7920 - 7924
[10] GEORGE DG, 1990, METHOD ENZYMOL, V183, P333

← 1 2 3 →