3,6-THIOANHYDRO SUGARS AS IMPORTANT KEY INTERMEDIATES IN THE ENANTIOSPECIFIC SYNTHESIS OF CHIRAL POLYHYDROXYTHIOLANES

被引：9

作者：

IZQUIERDO, I

PLAZA, MT

ASENJO, R

RODRIGUEZ, M

机构：

[1] Department of Organic Chemistry, Faculty of Pharmacy, University of Granada

来源：

TETRAHEDRON-ASYMMETRY | 1995年 / 6卷 / 05期

关键词：

D O I：

10.1016/0957-4166(95)00137-E

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Methyl 3,6-thioanhydro-alpha-D-glucopyranoside (5) was obtained in seven steps from the commercially available methyl alpha-D-glucopyranoside. Transformation of 5 into (2R,3R,4S)-3,4-dihydroxy-2-[(S)-1,2-dihydroxyethyl]th (9) was achieved by acid hydrolysis and subsequent reduction without isolation of its formyl derivative (8).

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页码：1117 / 1122

页数：6

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