A GRAPHIC DIGITAL DATABASE OF DROSOPHILA EMBRYOGENESIS

被引：10

作者：

HARTENSTEIN, V ^{[1
]}

LEE, A ^{[1
]}

TOGA, AW ^{[1
]}

机构：

[1] UNIV CALIF LOS ANGELES,DEPT NEUROL,DEPT NEUROL IMAGING,LOS ANGELES,CA 90024

来源：

TRENDS IN GENETICS | 1995年 / 11卷 / 02期

关键词：

D O I：

10.1016/S0168-9525(00)88997-0

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Modern studies of the genetic control of development have increased the need for an accurate and comprehensive storage and display of gene expression data. This can be achieved in the form of an electronic graphic database of development. Here, we introduce the first steps towards a database of Drosophila embryogenesis. For each morphologically defined stage, a complete series of histological and/or optical sections are generated (optical sections are generated by laser confocal microscopy). Digitized sections are imported into a drawing program where they serve as templates to define the contours of organs and the position of individual cells. From these data, surface and point cloud models of all developmental stages are generated. Gene expression data can be entered by translating the expression domain of a given gene into the three-dimensional coordinate system of the database.

引用

页码：51 / 58

页数：8

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