ANTIBODIES DIRECTED AGAINST BRUSH-BORDER ANTIGENS OF PROXIMAL TUBULES IN RENAL-ALLOGRAFT RECIPIENTS

被引：24

作者：

PAUL, LC

STUFFERSHEIMAN, M

VANES, LA

DEGRAEFF, J

机构：

[1] Department of Nephrology, University Hospital, Leiden

来源：

CLINICAL IMMUNOLOGY AND IMMUNOPATHOLOGY | 1979年 / 14卷 / 02期

关键词：

D O I：

10.1016/0090-1229(79)90145-4

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In two renal allograft recipients, antibodies directed against renal tubular epithelial (RTE) antigens of the graft developed after transplantation. The anti-RTE antibodies were found after graft nephrectomy in one recipient. In the other recipient these antibodies were demonstrated 3 months after transplantation. The anti-RTE activity in the sera of this recipient could be absorbed with tubular epithelial antigen from urine, which is known to induce autologous immune complex nephritis in rats. The recipient, however, did not develop immune complex glomerulonephritis. © 1979.

引用

页码：238 / 243

页数：6

共 26 条

[1] EXPERIMENTAL GLOMERULONEPHRITIS IN ISOLATED PERFUSED RAT-KIDNEY [J].