EFFECT OF CLINDAMYCIN ON PNEUMONIA FROM REACTIVATION OF TOXOPLASMA-GONDII INFECTION IN MICE

被引:13
作者
FILICE, GA [1 ]
POMEROY, C [1 ]
机构
[1] UNIV MINNESOTA,DEPT MED,DIV INFECT DIS,MINNEAPOLIS,MN 55455
关键词
D O I
10.1128/AAC.35.4.780
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Clindamycin was used to treat the reactivation of a chronic Toxoplasma gondii infection in mice. Clindamycin reduced mortality by 44% when used prophylactically (P < 0.001) but appeared to be less effective when used to treat clinically apparent reactivation. Further studies should be conducted to establish the efficacy of clindamycin for the treatment of toxoplasmosis in humans.
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页码:780 / 782
页数:3
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