GLYCINE PRODRUG FACILITATES MEMORY RETRIEVAL IN HUMANS

被引：73

作者：

SCHWARTZ, BL

HASHTROUDI, S

HERTING, RL

HANDERSON, H

DEUTSCH, SI

机构：

[1] DEPT VET AFFAIRS MED CTR,PSYCHIAT SERV 116A,50 IRVING ST NW,WASHINGTON,DC 20422

[2] VET ADM MED CTR,WASHINGTON,DC 20422

[3] GEORGETOWN UNIV,WASHINGTON,DC 20007

[4] GEORGE WASHINGTON UNIV,WASHINGTON,DC 20052

[5] SEARLE RES & DEV,WASHINGTON,DC

来源：

NEUROLOGY | 1991年 / 41卷 / 09期

关键词：

D O I：

10.1212/WNL.41.9.1341

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Modulation of glycine concentrations in the brain influences learning and memory functions in experimental animals. We administered milacemide, a glycine prodrug, or placebo to young and older healthy adults, who performed a word-retrieval task. Milacemide administration increased the number of words retrieved and decreased the latency with which these words were retrieved for both young and older adults.

引用

页码：1341 / 1343

页数：3

共 30 条

[1] LONG-TERM POTENTIATION AND NMDA RECEPTORS IN RAT VISUAL-CORTEX [J].