METABOLIC SWITCHING IN CYTOCHROME-P-450CAM - DEUTERIUM-ISOTOPE EFFECTS ON REGIOSPECIFICITY AND THE MONOOXYGENASE OXIDASE RATIO

被引：131

作者：

ATKINS, WM

SLIGAR, SG

机构：

[1] UNIV ILLINOIS, DEPT BIOCHEM, URBANA, IL 61801 USA

[2] UNIV ILLINOIS, DEPT CHEM, URBANA, IL 61801 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1987年 / 109卷 / 12期

关键词：

D O I：

10.1021/ja00246a038

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

收藏

页码：3754 / 3760

页数：7

相关论文

共 28 条

[1] TRI-TERT-BUTYLETHYLENE
ABRUSCAT.GJ
TIDWELL, TT
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1970, 92 (13) : 4125 - &
[2] REARRANGEMENTS OF NORBORNENCE OXIDE
CRANDALL, JK
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1964, 29 (10) : 2830 - &
[3] EBLE KS, 1984, J BIOL CHEM, V259, P4389
[4] TYROSINE MOTIONS IN RELATION TO THE FERRIC SPIN EQUILIBRIUM OF CYTOCHROME-P-450CAM
FISHER, MT
SLIGAR, SG
[J]. BIOCHEMISTRY, 1985, 24 (23) : 6696 - 6701
[5] SYNTHESIS OF EXO,EXO-5,6-DIDEUTERIO-SYN-7-ACETOXYNORBORNENE AND EXO,EXO-5,6-DIDEUTERIO-2-NORBORENE
FRANZUS, B
BAIRD, WC
SURRIDGE, JH
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1968, 33 (03) : 1288 - &
[6] STEREOCHEMISTRY AND DEUTERIUM-ISOTOPE EFFECTS IN CAMPHOR HYDROXYLATION BY THE CYTOCHROME P450CAM MONOXYGENASE SYSTEM
GELB, MH
HEIMBROOK, DC
MALKONEN, P
SLIGAR, SG
[J]. BIOCHEMISTRY, 1982, 21 (02) : 370 - 377
[7] GORSKY LD, 1984, J BIOL CHEM, V259, P6812
[8] ALIPHATIC HYDROXYLATION BY HIGHLY PURIFIED LIVER MICROSOMAL CYTOCHROME-P-450 - EVIDENCE FOR A CARBON RADICAL INTERMEDIATE
GROVES, JT
MCCLUSKY, GA
WHITE, RE
COON, MJ
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1978, 81 (01) : 154 - 160
[9] Gunsalus I C, 1978, Methods Enzymol, V52, P166
[10] HARADA N, 1984, J BIOL CHEM, V259, P3005