DECREASE OF INHIBITORY DRIVING FORCE IN CRAYFISH STRETCH RECEPTION - MECHANISM OF THE CONVULSANT ACTION OF PENICILLIN

被引：10

作者：

DEISZ, RA ^{[1
]}

AICKIN, CC ^{[1
]}

LUX, HD ^{[1
]}

机构：

[1] MAX PLANCK INST PSYCHIAT,DEPT NEUROPHYSIOL,D-8000 MUNICH 40,FED REP GER

来源：

NEUROSCIENCE LETTERS | 1979年 / 11卷 / 03期

关键词：

D O I：

10.1016/0304-3940(79)90020-X

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The effect of penicillin on the evoked IPSP was investigated in the isolated crayfish stretch receptor. The IPSP driving force (IPSP reversal potential minus membrane potential) was reduced in a dose-dependent fashion but, when necessary correction was made for the decrease in resting membrane conductance, the synaptic conductance was only slightly reduced. The possibility that a penicillin-induced intracellular acidification was responsible for the decrease in IPSP driving force is considered. © 1979.

引用

页码：347 / 352

页数：6

共 23 条

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