CHARACTERIZATION OF ALPHA-1-ANTITRYPSIN BY ISOELECTRIC-FOCUSING ON AN ULTRATHIN POLYACRYLAMIDE-GEL LAYER - ECONOMIC HIGH-RESOLUTION SYSTEM FOR DETERMINING PIM SUBTYPES

被引：24

作者：

MASSI, G ^{[1
]}

FABIANO, A ^{[1
]}

RAGUSA, D ^{[1
]}

AUCONI, P ^{[1
]}

机构：

[1] ENTE OSPED AREZZO,DIV PEDIAT,AREZZO,ITALY

来源：

HUMAN GENETICS | 1979年 / 53卷 / 01期

关键词：

D O I：

10.1007/BF00289456

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Through the use of ultrathin layer polyacrylamide gel isoelectric focusing it is possible to obtain a resolution of the bands of α1AT so as to be able to easily recognize all six PiM subtypes. The optimal resolution of the PiM subtypes is obtained without deforming the pattern of the Pi phenotypes. In addition to high resolution, ultrathin layer polyacrylamide gel isoelectric focusing permits a notable reduction of fees to 1/5 of the usual. © 1979 Springer-Verlag.

引用

页码：91 / 95

页数：5

共 16 条

[1] ALLEN RC, 1974, AM J CLIN PATHOL, V62, P732
[2] CONSTANS J, 1975, CR ACAD SCI D NAT, V281, P1361
[3] GENETICS OF ALPHA1-ANTITRYPSIN - FAMILY STUDY IN ENGLAND AND SCOTLAND
COOK, PJL
[J]. ANNALS OF HUMAN GENETICS, 1975, 38 (JAN) : 275 - 287
[4] SERUM PREALBUMIN - POLYMORPHISM IN MAN
FAGERHOL, MK
BRAEND, M
[J]. SCIENCE, 1965, 149 (3687) : 986 - &
[5] ALPHA1-ANTITRYPSIN - COMMON SUBTYPES OF PI M
FRANTS, RR
ERIKSSON, AW
[J]. HUMAN HEREDITY, 1976, 26 (06) : 435 - 440
[6] RELIABLE CLASSIFICATION OF 6 PI M SUBTYPES BY SEPARATOR ISOELECTRIC-FOCUSING
FRANTS, RR
ERIKSSON, AW
[J]. HUMAN HEREDITY, 1978, 28 (03) : 201 - 209
[7] SEPARATOR ISOELECTRIC-FOCUSING FOR IDENTIFICATION OF ALPHA-L-ANTITRYPSIN (PIM) SUBTYPES
FRANTS, RR
NOORDHOEK, GT
ERIKSSON, AW
[J]. SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION, 1978, 38 (05) : 457 - 462
[8] CLASSIFICATION OF ALPHA-1-ANTITRYPSIN (PI) PHENOTYPES BY ISOELECTROFOCUSING - DISTINCTION OF 6 SUBTYPES OF PIM PHENOTYPE
GENZ, T
MARTIN, JP
CLEVE, H
[J]. HUMAN GENETICS, 1977, 38 (03) : 325 - 332
[9] ULTRA-THIN-LAYER ISOELECTRIC-FOCUSING IN POLYACRYLAMIDE GELS ON CELLOPHANE
GORG, A
POSTEL, W
WESTERMEIER, R
[J]. ANALYTICAL BIOCHEMISTRY, 1978, 89 (01) : 60 - 70
[10] POPULATION-GENETICS OF ALPHA1-ANTITRYPSIN IN NETHERLANDS - DESCRIPTION OF A NEW ELECTROPHORETIC VARIANT
KLASEN, EC
FRANKEN, C
VOLKERS, WS
BERNINI, LF
[J]. HUMAN GENETICS, 1977, 37 (03) : 303 - 313

← 1 2 →