STUDIES ON SYNTHESES OF HETEROCYCLIC COMPOUNDS .279. SYNTHESIS OF O-ISOBUTYLCULARIDINE

被引：4

作者：

KAMETANI, T

IIDA, H

KIBAYASHI, C

机构：

[1] Pharmaceutical Institute, School of Medicine, Tohoku University, Tokyo College of Pharmacy, Sendai

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1969年 / 6卷 / 01期

关键词：

D O I：

10.1002/jhet.5570060111

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Although various methods of oxepine formation from phenoxybenzene dicarboxylic acids was attempted, only 11‐hydroxy‐4‐isobutoxy‐7,8‐dimethoxydibenz[b,f]oxepin‐l‐ylaeetic acid lactone (XXX) was synthesized successfully. Compound XXX gave O‐isobutylcularidine (XXXVlIb) in a few steps. Our synthetic O‐isobutylcularidine was identical with that prepared from natural cularidine proving the structure for cularidine proposed by Manske. However, dealkylation of synthetic O‐isobutylcularidine was unsuccessful. Copyright © 1969 Journal of Heterocyclic Chemistry

引用

页码：61 / +

页数：1

共 14 条

[1] CONFIGURATION AND CONFORMATION OF CULARINE [J].