ADDITION OF CARBON RADICALS TO 4',5'-UNSATURATED URACILNUCLEOSIDES BY THE USE OF ORGANOSELENIUM REAGENTS - A NEW STEREOSELECTIVE ENTRY TO C-C BOND FORMATION AT THE 5'-POSITION

被引：33

作者：

HARAGUCHI, K ^{[1
]}

TANAKA, H ^{[1
]}

MIYASAKA, T ^{[1
]}

机构：

[1] SHOWA UNIV,SCH PHARMACEUT SCI,HATANODAI 1-5-8,SHINAGAWA KU,TOKYO 142,JAPAN

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 02期

关键词：

D O I：

10.1016/S0040-4039(00)94378-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Addition of carbon radicals generated from organoselenium reagents (PhSeR: R= COPh, CO2Et, CH2CO2Et, CH2COMe, and CH2CN) to 4′,5′-unsaturated uracilnucleosides was found to provide a highly efficient entry to CC bond formation at the 5′-position, the stereochemical outcome of which is dependent upon the hydroxyl protecting group. © 1990.

引用

页码：227 / 230

页数：4

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