ROLE OF SEROTONIN IN THE CONTROL OF PEDAL CILIARY ACTIVITY BY IDENTIFIED NEURONS IN TRITONIA-DIOMEDEA

被引:81
作者
AUDESIRK, G [1 ]
MCCAMAN, RE [1 ]
DENNISWILLOWS, AO [1 ]
机构
[1] CITY HOPE NATL MED CTR,DUARTE,CA 91010
来源
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY | 1979年 / 62卷 / 01期
基金
美国国家科学基金会;
关键词
D O I
10.1016/0306-4492(79)90104-7
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
1. A pair of identified neurons (Pd 21) in the pedal ganglia of Tritonia diomedea are capable of exciting pedal ciliary beating. 2. These neurons contain serotonin, but not acetylcholine, dopamine, norepinephrine or histamine. Other identifiable serotonergic neurons are also found in the Tritonia brain. 3. Serotonin (10-7 g/ml) excites ciliary beating in isolated foot strips bathed in a high Mg2+-low Ca2+ solution. 4. Serotonin injected into intact Tritonia prolonged pedal ciliary beating. 5. The Pd 21 neurons probably release serotonin into spaces in the foot, where the serotonin exerts its excitatory effect on the ciliated cells. © 1979.
引用
收藏
页码:87 / 91
页数:5
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