DOMINANT ROLE FOR TISSUE BINDING IN 1ST-PASS EXTRACTION OF IMIPRAMINE BY PERFUSED RAT-LIVER

被引：23

作者：

STEGMANN, R ^{[1
]}

BICKEL, MH ^{[1
]}

机构：

[1] UNIV BERN,INST MED CHEM,CH-3001 BERN,SWITZERLAND

来源：

XENOBIOTICA | 1977年 / 7卷 / 12期

关键词：

D O I：

10.3109/00498257709038703

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：737 / 746

页数：10

共 20 条

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[3] BINDING OF BASIC AND ACIDIC DRUGS TO RAT TISSUE SUBCELLULAR-FRACTIONS [J].

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[4]

BICKEL MH, 1968, ARCH INT PHARMACOD T, V173, P433

[5] UPTAKE, SUBCELLULAR-DISTRIBUTION, AND TRANSFER PROCESSES OF IMIPRAMINE AND ITS METABOLITES FORMED IN RAT-LIVER PERFUSION SYSTEMS [J].

BICKEL, MH ;

BORNER, H .

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[6] MEMBRANE LIPIDS AS INTRACELLULAR BINDERS OF CHLORPROMAZINE AND RELATED DRUGS [J].

DIFRANCESCO, C ;

BICKEL, MH .

CHEMICO-BIOLOGICAL INTERACTIONS, 1977, 16 (03) :335-346

[7] CONCENTRATION OF (+ OR -)-PROPRANOLOL IN ISOLATED, PERFUSED LUNGS OF RAT [J].

DOLLERY, CT ;

JUNOD, AF .

BRITISH JOURNAL OF PHARMACOLOGY, 1976, 57 (01) :67-71

[8]

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[9]

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[10]

EVANS GH, 1973, J PHARMACOL EXP THER, V186, P447

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