SYNTHESIS OF CHLOROPYRIMIDINYLMETHYLENEPHOSPHORANES AND THEIR WITTIG REACTIONS WITH ALDEHYDES

被引：14

作者：

KATO, T

KATAGIRI, N

TAKAHASHI, T

KATAGIRI, Y

机构：

[1] Pharmaceutical Institute, Tohoku University, Sendai, 980, Aobayama

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1979年 / 16卷 / 08期

关键词：

D O I：

10.1002/jhet.5570160812

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Methylpyrimidines were treated with phosphorus pentachloride in phosphorus oxychloride to give trichloromethylpyrimidines, which reacted with two equivalent amounts of triphenylphosphine to yield chloropyrimidinylmethylenetriphenylphosphoranes as stable ylides in one step. These phosphorus ylides were subjected to the Wittig reaction with a variety of aldehydes to afford chloropyrimidinylolefins. Copyright © 1979 Journal of Heterocyclic Chemistry

引用

页码：1575 / 1578

页数：4

共 10 条

[1]

Bredereck H, 1973, ORG SYNTH, V5, P794

[2]

COREY EJ, 1972, TETRAHEDRON LETT, P3769

[3] PHOTODIMERIZATION OF 3-METHYL-4-NITRO-5-STYRYLISOXAZOLE IN SOLID-STATE [J].