DNA - A MODEL-COMPOUND FOR SOLUTION STUDIES OF MACROMOLECULES

被引：66

作者：

PECORA, R

机构：

[1] Department of Chemistry, Stanford University, Stanford

来源：

SCIENCE | 1991年 / 251卷 / 4996期

关键词：

D O I：

10.1126/science.2000490

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Well-defined, monodisperse, homologous series of oligonucleotides and DNA restriction fragments may now be produced and used as models of rigid and semirigid rodlike molecules in solution. Information from optical experiments on these model systems aids in the formulation and testing of theories of macromolecular dynamics in both dilute and concentrated solution.

引用

页码：893 / 898

页数：6

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[1] BROWNIAN DYNAMICS SIMULATIONS OF WORMLIKE CHAINS - DYNAMIC LIGHT-SCATTERING FROM A 2311 BASE PAIR DNA FRAGMENT [J].