METHIONINE ENKEPHALIN AND MORPHINE ALTER MONO-AMINE AND CYCLIC NUCLEOTIDE LEVELS IN THE CEREBRAL GANGLIA OF THE FRESHWATER BIVALVE ANODONTA-CYGNEA

被引：46

作者：

STEFANO, GB ^{[1
]}

HIRIPI, L ^{[1
]}

机构：

[1] HUNGARIAN ACAD SCI,BIOL RES INST,TIHANY,HUNGARY

来源：

LIFE SCIENCES | 1979年 / 25卷 / 03期

关键词：

D O I：

10.1016/0024-3205(79)90298-4

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Methionine enkephalin and morphine increased dopamine levels in the cerebral ganglia of Anodonta cygnea. Both agents increased the levels of C'GMP and depressed the levels of C'AMP. The pharmacological effect on dopamine and cyclic nucleotide levels were blocked by prior treatments of the cerebral ganglia with naloxone. The study demonstrates pharmacologically the possible existence of an opiate receptor mechanism. © 1979.

引用

页码：291 / 297

页数：7

共 29 条

[1] PEPTIDE REGULATION OF BURSTING PACEMAKER ACTIVITY IN A MOLLUSCAN NEUROSECRETORY CELL [J].