MICROSCOPIC STUDY OF INCREASED VASCULAR-PERMEABILITY AND LEUKOCYTE EMIGRATION IN THE CHICKEN WING WEB

The components of an acute inflammatory response in the chicken were investigated using a combination of histological and colloidal carbon techniques. The experimental model was the inflammatory reaction induced by the s.c. injection of turpentine or carrageenin into the wing web. Increased vascular permeability was shown to be mainly venular in origin. There did not appear to be an ordered migration of heterophils and monocytes and the process was unrelated to altered vascular permeability. Special features distinct from acute mammalian inflammation included a basophilic response, giant cell formation and the development of perivascular lymphoid foci.