MICROBICIDAL FUNCTION OF THE NEUTROPHILS IN HAIRY-CELL LEUKEMIA

被引：18

作者：

CHILD, JA

CAWLEY, JC

MARTIN, S

GHONEIM, ATM

机构：

[1] GEN INFIRM,DEPT MED,LEEDS LS1 3EX,W YORKSHIRE,ENGLAND

[2] UNIV LEEDS,SCH MED,DEPT MICROBIOL,LEEDS LS2 9JT,W YORKSHIRE,ENGLAND

来源：

ACTA HAEMATOLOGICA | 1979年 / 62卷 / 04期

关键词：

D O I：

10.1159/000207571

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The ability of neutrophils from patients with hairy-cell leukaemia to kill Candida guilliermondii and Staphylococcus aureus in vitro was investigated. Of 10 patients, 8 showed defective candida killing, 5 defective bacteria killing, in comparison with normal controls. Study of those patients who underwent splenectomy suggests that neutrophil function can be improved by splenectomy. The possible causes of defective function in this disease are discussed.

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页码：191 / 198

页数：8

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