INTERLEUKIN-1 ADMINISTRATION TO C3H HEJ MICE AFTER BUT NOT PRIOR TO INFECTION INCREASES RESISTANCE TO SALMONELLA-TYPHIMURIUM

被引：21

作者：

MORRISSEY, PJ

CHARRIER, K

机构：

来源：

INFECTION AND IMMUNITY | 1991年 / 59卷 / 12期

关键词：

D O I：

10.1128/IAI.59.12.4729-4731.1991

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Interleukin-1 (IL-1) treatment of C3H/HeN and C3H/HeJ mice prior to infection with Salmonella typhimurium increased the survival fraction only in C3H/HeN mice. IL-1 administration after infection resulted in a significant increase in mean survival time in C3H/HeJ but not C3H/HeN mice. Bacterial growth in IL-1-treated C3H/HeJ mice was less than that in control mice.

引用

页码：4729 / 4731

页数：3

共 23 条

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