Oncogenes and anti-oncogenes

被引：28

作者：

Cooper, J. A. ^{[1
]}

机构：

[1] Fred Hutchinson Canc Res Ctr, Seattle, WA 98104 USA

来源：

CURRENT OPINION IN CELL BIOLOGY | 1990年 / 2卷 / 02期

关键词：

D O I：

10.1016/0955-0674(90)90021-6

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The study of oncogenes offers insights into many steps in signal transduction. Rapid progress is possible because of the combination of biochemistry and genetics-unique in vertebrate cell biology-the availability of specific clones and antibodies, sequence information, dominant mutants, and biochemical assays of function. The wealth of detail on oncogenes and proto-oncogenes continues to increase dramatically. Hopefully, in the next year or two some of the gaps will be filled in and all the steps along at least one pathway from the cell membrane to the nucleus will be understood. © 1990.

引用

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页码：285 / 295

页数：11

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