DISTRIBUTION OF TECHNETIUM-99M AND JODINE-131 IN GASTRIC MUCOSA - A TECHNIQUE TO DETERMINE MICROHISTOAUTORADIOGRAPHICAL DISTRIBUTION OF WATER SOLUBLE ISOTOPES

被引:27
作者
MEIERRUGE, W
FRIDRICH, R
机构
[1] der Nuklearmedizinischen Abteilung, des Röntgeninstituts der Universität Basel
[2] Abteilung für experimentelle Pathologie und Histochemie Sandoz AG, Basel
来源
HISTOCHEMIE | 1969年 / 19卷 / 02期
关键词
D O I
10.1007/BF00281094
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
A method for microhistoautoradiographic examination of water soluble radioactive isotopes and its use in studying the distribution of 131J and 99mTc in the gastric mucosa is described. It is shown that technetium is selectively secreted by the parietal cells of the gastric mucosa. In contrast 131J is secreted by the chief and mucosal cells. The selective accumulation of 99mTc in the parietal cells suggests that technetium is secreted via a metabolic pathway. The main activity of 99mTc is observed in the gastric fundus. The distribution of both isotopes within the submucous lymphoid and capillary vessels of the antrum and fundus is equal. The microhistoautoradiographic results in the different parts of the stomach are confirmed by quantitative scintillation counting. © 1969 Springer-Verlag.
引用
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页码:147 / +
页数:1
相关论文
共 26 条
[1]   COMPARISON OF CONCENTRATING ABILITY OF HUMAN SALIVARY GLAND FOR BROMINE IODINE AND TECHNETIUM [J].
ALEXANDER, WD ;
HARDEN, RMG ;
MASON, DK ;
SHIMMINS, J ;
KOSTALAS, H .
ARCHIVES OF ORAL BIOLOGY, 1966, 11 (11) :1205-+
[3]  
BARDFELD PHILIP A., 1967, AMER J MED SCI, V254, P542
[4]  
Bartelink A, 1967, Ned Tijdschr Geneeskd, V111, P1105
[5]  
Borner W, 1965, Med Welt, V42, P2378
[6]  
BORNER W, 1967, MED WELT, V18, P2282
[7]  
BOSQUE PG, 1964, 2 INT C HIST CYT FRA, P188
[8]   DRY, HIGH RESOLUTION AUTORADIOGRAPHY [J].
BRANTON, D ;
JACOBSON, L .
STAIN TECHNOLOGY, 1962, 37 (04) :239-&
[9]  
ENGELHART G, 1968, SCHWEIZ MED WSCHR, V98, P301
[10]   FOUNDATIONS OF GASTRIC SCINTIGRAPHY WITH TECHNETIUM-99M AND FIRST EXPERIENCES IN ROUTINE CLINICAL OPERATIONS [J].
FRIDRICH, R ;
ENGELHART, G .
FORTSCHRITTE AUF DEM GEBIETE DER RONTGENSTRAHLEN UND DER NUKLEARMEDIZIN, 1969, 110 (03) :328-+