MOLECULAR-CLONING AND SEQUENCING OF CDNA-ENCODING URINARY STONE PROTEIN, WHICH IS IDENTICAL TO OSTEOPONTIN

被引：106

作者：

KOHRI, K

SUZUKI, Y

YOSHIDA, K

YAMAMOTO, K

AMASAKI, N

YAMATE, T

UMEKAWA, T

IGUCHI, M

SINOHARA, H

KURITA, T

机构：

[1] Department of Urology and Biochemistry, School of Medicine, Kinki University, Osaka

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1992年 / 184卷 / 02期

关键词：

D O I：

10.1016/0006-291X(92)90669-C

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We have sequenced a cDNA of urinary stone protein. cDNA sequences show complete homology between urinary stone protein and human osteopontin(bone sialoprotein) (nucleotides 265-886 and 1183-1424). Osteopontin is a recently discovered bone matrix protein which has been implicated in mediating mineral formation within bone extracellular matrix. This result shows that osteopontin is presumably involved in stone formation as stone matrix. © 1992.

引用

页码：859 / 864

页数：6

共 30 条

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