CHANGES IN INGESTIVE BEHAVIORS AND BODY-WEIGHT FOLLOWING INTRACRANIAL APPLICATION OF 17-ALPHA-ESTRADIOL

被引：14

作者：

BUTERA, PC ^{[1
]}

BEIKIRCH, RJ ^{[1
]}

WILLARD, DM ^{[1
]}

机构：

[1] NIAGARA UNIV,DEPT BIOL,NIAGARA,NY 14109

来源：

PHYSIOLOGY & BEHAVIOR | 1990年 / 47卷 / 06期

关键词：

17; α-Estradiol; Body weight; Food intake; Paraventricular nucleus; Stereoisomers;

D O I：

10.1016/0031-9384(90)90386-I

中图分类号：

B84 [心理学];

学科分类号：

04 [教育学]; 0402 [心理学];

摘要：

The present experiment was conducted to determine if central implants of 17 α-estradiol could influence food intake, water intake, and body weight in ovariectomized rats. A total of fifteen animals were fitted with bilateral guide cannulae in the paraventricular nucleus (PVN) and stimulated unilaterally with cholesterol and 17 α-estradiol in each side of the brain. Compared with cholesterol treatment, 17 α-estradiol implants in the PVN significantly lowered food intake and body weight but did not affect water intake. These findings indicate that the PVN is a brain region responsive to the effects of 17 α-estradiol on feeding behavior, and support the hypothesis that the effects of estrogens on ingestive and reproductive behaviors are organized separately within the brain. © 1990.

引用

页码：1291 / 1293

页数：3

共 19 条

[1]

[Anonymous], 1979, STEREOTAXIC ATLAS RA

[2]

BALL P, 1980, Acta Endocrinologica Supplementum, V93, P1

[3]

INTRACRANIAL ESTRADIOL IN OVARIECTOMIZED GUINEA-PIGS - EFFECTS ON INGESTIVE BEHAVIORS AND BODY-WEIGHT [J].