THE KAPURIMYCINS, NEW ANTITUMOR ANTIBIOTICS PRODUCED BY STREPTOMYCES - PHYSICOCHEMICAL PROPERTIES AND STRUCTURE DETERMINATION

被引：11

作者：

YOSHIDA, M

HARA, M

SAITOH, Y

SANO, H

机构：

[1] Tokyo Research Laboratories, Kyowa Hakko Kogyo Co., Ltd., Machida, Tokyo 194

来源：

JOURNAL OF ANTIBIOTICS | 1990年 / 43卷 / 12期

关键词：

D O I：

10.7164/antibiotics.43.1519

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The kapurimycins A1, A2 and A3 were revealed to be new antitumor antibiotics with molecular formula of C27H26O9, C26H24O9 and C27H24O9, respectively. The structures of the kapurimycins were determined by NMR spectroscopic analysis. The kapurimycins are new class of polycyclic microbial metabolites having the tetrahydroanthra-gamma-pyrone skeleton and the beta,gamma-unsaturated delta-keto carboxylic acid structure. The individual components of the kapurimycins differ from one another in the side chain at the pyrone ring of the molecule.

引用

页码：1519 / 1523

页数：5

共 7 条

[1] STRUCTURE AND CHEMISTRY OF KIDAMYCIN [J].