EFFECTS OF PARASYMPATHECTOMY ON ANDROGEN RESPONSES OF THE RAT SUBMANDIBULAR-GLAND

被引:8
作者
KATSUKAWA, H
NINOMIYA, Y
FUNAKOSHI, M
机构
[1] Department of Oral Physiology, Asahi University School of Dentistry, Motosu-gun, Gifu, 501-02, Hozumi-cho
关键词
androgen metabolism; androgens; parasympathectomy; submandibular gland;
D O I
10.1016/0003-9969(90)90042-9
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
The effects of androgen on the activities of esteropeptidase and Δ4-3-ketosteroid 5α-reductase were investigated. Ratios of the denervated side to the non-operated side for gland weight and esteropeptidase activity were higher in androgenized females than in untreated females. The specific activities of 5α-reductase were increased by denervation but the total activities were decreased. The results suggest that parasympathectomy leads to higher androgen responsiveness in the rat submandibular gland, which relates to the observed reduction in weight loss of the gland and the increases in its esteropeptidase activities. © 1990.
引用
收藏
页码:273 / 275
页数:3
相关论文
共 13 条
[1]  
Chretien M, 1977, Int Rev Cytol, V50, P333
[2]  
EMMELIN N, 1979, CHANGED INTERACTIVE, P5
[3]   PREPARATION AND PROPERTIES OF 2 NEW CHROMOGENIC SUBSTRATES OF TRYPSIN [J].
ERLANGER, BF ;
COHEN, W ;
KOKOWSKY, N .
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1961, 95 (02) :271-&
[5]   EFFECTS OF PROLONGED DUCT LIGATION OF THE RAT SALIVARY-GLANDS ON THE ACTIVITY OF TRYPSIN-LIKE PROTEASE [J].
IKENO, K ;
SAIKATSU, S ;
UNO, T ;
IKENO, T .
ARCHIVES OF ORAL BIOLOGY, 1988, 33 (08) :613-615
[6]  
KATSUKAWA H, 1980, Japanese Journal of Zootechnical Science, V51, P165
[7]  
KATSUKAWA H, 1980, Japanese Journal of Zootechnical Science, V51, P159
[8]   EFFECTS OF ANDROGENS ON THE ACTIVITY OF STEROID-METABOLIZING ENZYMES IN THE MURINE SUBMAXILLARY-GLAND [J].
KATSUKAWA, H ;
TANABE, Y ;
FUNAKOSHI, M .
JOURNAL OF DENTAL RESEARCH, 1983, 62 (06) :725-727
[9]  
Lacassagne A, 1941, CR SOC BIOL, V135, P241
[10]  
LEIDL W, 1982, CRC HDB ENDOCRINOLOG, P145