EFFECTS OF EXTERNAL CALCIUM-IONS AND STRONTIUM IONS ON INTERACTIONS OF ISOPRENALINE AND ITS COMPETITIVE INHIBITOR WITH BETA-ADRENOCEPTORS IN THE INTESTINAL SMOOTH-MUSCLE

被引：2

作者：

TAKAYANAGI, I ^{[1
]}

TAKAGI, K ^{[1
]}

机构：

[1] SCI UNIV TOKYO, FAC PHARMACEUT SCI, DEPT PHARMACOTHERAPEUT, TOKYO 162, JAPAN

来源：

EUROPEAN JOURNAL OF PHARMACOLOGY | 1979年 / 55卷 / 04期

关键词：

Ca ions; Drug-β-adrenoceptor interaction; Sr ions;

D O I：

10.1016/0014-2999(79)90114-6

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The effects were tested to Ca ions and Sr ions on interactions of isoprenaline and its competitive inhibitor with β-adrenoceptors in the taenia caecum from the guinea pig. Ca ions were involved in the combination of isoprenaline with the β-adrenoceptors but not involved in the combination of the competitive inhibitor with the β-adrenoceptors. Sr ions could not substitute for Ca ions in the isoprenaline-receptor interaction. © 1979.

引用

页码：397 / 399

页数：3

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