CHROMATOGRAPHY OF CALCIUM-CHANNEL BLOCKERS

被引：26

作者：

AHNOFF, M

PERSSON, BA

机构：

来源：

JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS | 1990年 / 531卷

关键词：

D O I：

10.1016/S0378-4347(00)82284-7

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Numerous publications during the past ten years have described the determination of various calcium channel blockers in biological fluids, using gas and liquid chromatographic techniques. Diltiazem, verapamil, flunarizine and a growing number of dihydropyridines belong to this group of drugs, which in most instances are active at low plasma concentrations. From a bioanalytical point of view these compounds have many features in common, such as high lipophilicity and favourable detection properties. © 1990.

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页码：181 / 213

页数：33

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