NUCLEOLAR ORGANIZING REGIONS (NORS) IN PLEOMORPHIC ADENOMAS OF THE SALIVARY-GLANDS

被引：22

作者：

LANDINI, G

机构：

[1] Department of Oral Pathology, Kagoshima University Dental School, Kagoshima

来源：

JOURNAL OF ORAL PATHOLOGY & MEDICINE | 1990年 / 19卷 / 06期

关键词：

adenoma; pleomorphic; chondroid tissue; nucleolar organizer region; salivary gland;

D O I：

10.1111/j.1600-0714.1990.tb00837.x

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

The number of nucleolar organizing regions (NORs) can be used to reveal the degree of cell activity or metabolism in histopathology specimens. Forty‐one cases of pleomorphic adenomas of the salivary glands were studied with a silver nitrate colloid staining method to demonstrate the NORs in the cells of the solid and duct pattern areas and in chondroid areas. Acinic and intercalated ducts cells of the surrounding normal salivary glands were also examined. The data was analyzed statistically and it was found that the cells in the solid/ductal areas had a higher cellular activity than the chondroid cells. This difference is probably directly related with the possibility of malignant transformation and the incidence of the different types of malignant pleomorphic adenomas. Furthermore, it is concluded that the number of NORs in pleomorphic adenomas to define malignancy should be done discriminating between the different histologic patterns because of their different metabolic activities. Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：257 / 260

页数：4

共 27 条

[1]

ALBERTS B, 1989, MOL BIOL CELL, P541

[2] SELECTIVE STAINING OF THE SAME SET OF NUCLEOLAR PHOSPHOPROTEINS BY SILVER AND GIEMSA - A COMBINED BIOCHEMICAL AND CYTOCHEMICAL STUDY ON STAINING OF NORS [J].