POSITIVE CORRELATION BETWEEN BREAST-CANCER INCIDENCE AND HLA ANTIGENS

被引:16
作者
BOUILLENNE, C
DENEUFBOURG, JM
机构
[1] HOP UNIV BAVIERE,SERV RADIOTHERAPIE,B-4000 LIEGE,BELGIUM
[2] UNIV LIEGE,TRANSFUS SANGUINE LAB,B-4000 LIEGE,BELGIUM
[3] UNIV LIEGE,SANGUINS GRP,B-4000 LIEGE,BELGIUM
关键词
D O I
10.1159/000225331
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
HLA determinations were made at the time of diagnosis among a lot of 141 patients with breast cancer. Values of relative risk as well as frequencies of antigens at the first and the second locus were confronted to data found in a control population. Subdivisions of the neoplastic population according to hormonal status and parity led to the mergence of significant differences: frequency of A28 in menopausal nulliparous women with breast cancer is 26 vs. 7% in controls (p corrected = 0.038) with relative risk = 6.63 (p 0.001).
引用
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页码:156 / 159
页数:4
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