HLA FREQUENCIES IN BLACK ZIMBABWEANS

被引：15

作者：

DUTOIT, ED ^{[1
]}

EMMANUEL, JC ^{[1
]}

WEST, G ^{[1
]}

TALJAARD, DG ^{[1
]}

OUDSHOORN, M ^{[1
]}

机构：

[1] BLOOD TRANSFUS SERV,HARARE,ZIMBABWE

来源：

TISSUE ANTIGENS | 1990年 / 36卷 / 03期

关键词：

genetics; HLA antigens; major histocompatibility complex; Population;

D O I：

10.1111/j.1399-0039.1990.tb01812.x

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Abstract: One‐hundred‐and‐nineteen normal Black Zimbabweans were typed for HLA antigens. We found a close similarity between the HLA antigen frequencies in Zimbabweans and Black South Africans (Xhosa), another Bantu‐speaking group. The only significant differences noted were for HLA‐Aw36, ‐Bw53, ‐Cw6, ‐DR4 and ‐DQw3 (p<0.0l). The most common HLA haplotypes in significant positive linkage disequilibrium in the two groups were different. The differences that were noted may be due to gene flow from the San to the Black South Africans, since it is thought that the Zimbabweans had little if any contact with the San. Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：122 / 124

页数：3

共 10 条

[1]

BODMER JG, 1977, HISTOCOMPATIBILITY T, P35

[2]

Cavalli-Sforza L. L., 1971, GENETICS HUMAN POPUL, P704

[3] THE HLA GENETIC CONSTITUTION OF THE BUSHMEN (SAN) [J].

DUTOIT, ED ;

TALJAARD, DG ;

MARSHALL, J ;

RITCHIE, C ;

OUDSHOORN, M .

HUMAN IMMUNOLOGY, 1990, 28 (04) :406-415

[4]

DUTOIT ED, 1988, TISSUE ANTIGENS, V31, P109

[5] GAMMAGLOBULIN GROUPS (GM AND INV) OF VARIOUS SOUTHERN AFRICAN POPULATIONS [J].

JENKINS, T ;

ZOUTENDYK, A ;

STEINBERG, AG .

AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY, 1970, 32 (02) :197-+

[6]

LOWE R F, 1981, Central African Journal of Medicine, V27, P1

[7]

MATTIUZ PL, 1970, HISTOCOMPATIBILITY T, P193

[8]

OKOYE RC, 1985, TISSUE ANTIGENS, V25, P142

[9] HLA-D REGION HETEROGENEITY IN A NIGERIAN POPULATION [J].

OKOYE, RC ;

OLLIER, W ;

JARAQUEMADA, D ;

AWAD, J ;

NAVARRETTE, C ;

CUTBUSH, S ;

CARTHY, D ;

DOSSANTOS, A ;

FESTENSTEIN, H .

TISSUE ANTIGENS, 1989, 33 (04) :445-456

[10]

TERASAKI PI, 1974, MANUAL TISSUE TYPING, P67

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