TREATMENT OF PAINFUL DIABETIC NEUROPATHY WITH CAPSAICIN 0.075-PERCENT

被引:69
作者
SCHEFFLER, NM
SHEITEL, PL
LIPTON, MN
机构
[1] American Center for Foot Health Research, Baltimore, 21227., MD
来源
JOURNAL OF THE AMERICAN PODIATRIC MEDICAL ASSOCIATION | 1991年 / 81卷 / 06期
关键词
D O I
10.7547/87507315-81-6-288
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
An 8-week, double-blind, vehicle-controlled study was conducted to determine the effectiveness of topical capsaicin 0.075% cream in relieving pain associated with diabetic neuropathy. Patients were selected who experienced moderate to very severe pain, which interfered with sleep or activities on a daily basis, and who were unresponsive or intolerant to conventional therapy. The results after 8 weeks showed a statistically significant difference in favor of the capsaicin-treated patients, with 90% of these patients improved. The results of this study indicate that topical capsaicin 0.075% cream is safe and effective in managing painful diabetic neuropathy.
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页码:288 / 293
页数:6
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