SYNTHESIS AND SOME TRANSFORMATIONS OF SUBSTITUTED 5,6-DIHYDRO-4H-1,3-OXAZINES

被引：20

作者：

KATRITZKY, AR ^{[1
]}

SHCHERBAKOVA, IV ^{[1
]}

TACK, RD ^{[1
]}

DAI, XQ ^{[1
]}

机构：

[1] EXXON CHEM LTD,DIV PARAMINS,ABINGDON,ENGLAND

来源：

TETRAHEDRON | 1993年 / 49卷 / 19期

关键词：

OLEFIN; AMIDOALKYLATION; 5,6-DIHYDRO-4H-1,3-OXAZINE; AMINE ADDITION; 3-HYDROXYPROPYLAMIDE;

D O I：

10.1016/S0040-4020(01)89906-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Substituted 5,6-hydro-4H-1,3-oxazines are prepared by the acid-catalyzed amidoalkylation of the terminal olefins. 5,6-Dihydro-4H-oxazines undergo further transformations involving the hetero-ring and/or the substituent leading to alkyl amino-substituted 5,6-dihydro-4H-1,3-dihydrooxazines and for to ring-opened products, 3-hydroxypropylamides.

引用

页码：3907 / 3918

页数：12

共 35 条

[1] NEW STEREOSPECIFIC SYNTHESIS OF 5,6-DIHYDRO-H-4-1,3-THIAZINES BY POLAR 1,4-CYCLOADDITION OF THIOAMIDOALKYL IONS TO OLEFINS - CONFIGURATIONAL AND CONFORMATIONAL NUCLEAR MAGNETIC-RESONANCE ANALYSIS OF PRODUCTS [J].