MUPIROCIN RESISTANCE IN COAGULASE-NEGATIVE STAPHYLOCOCCI

被引：19

作者：

CONNOLLY, S ^{[1
]}

NOBLE, WC ^{[1
]}

PHILLIPS, I ^{[1
]}

机构：

[1] UNITED MED DENT SCH,DIV MICROBIOL,LONDON SE1 7EH,ENGLAND

来源：

JOURNAL OF MEDICAL MICROBIOLOGY | 1993年 / 39卷 / 06期

关键词：

D O I：

10.1099/00222615-39-6-450

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

High-level mupirocin resistance in coagulase-negative staphylococci isolated from patients undergoing peritoneal dialysis was investigated by transfer of the resistance determinants, usually in the form of a plasmid, to Staphylococcus aureus strains, cleavage of the plasmid by restriction endonuclease and hybridisation with a probe comprising a 4.05 kb EcoRI fragment of a plasmid from a S. aureus strain. In most instances the mupirocin-resistant staphylococci isolated from each patient were different according to the species, antibiogram and plasmid profile data. The mupirocin resistance determinant was carried on various plasmids as judged by EcoRI restriction fragment length polymorphisms. All hybridised at about 4 kb with the S. aureus probe.

引用

页码：450 / 453

页数：4

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