TRANSPLANTATION OF PEDIATRIC CADAVER KIDNEYS INTO ADULT RECIPIENTS

被引：40

作者：

GOURLAY, W ^{[1
]}

STOTHERS, L ^{[1
]}

MCLOUGHLIN, MG ^{[1
]}

MANSON, AD ^{[1
]}

KEOWN, P ^{[1
]}

机构：

[1] UNIV BRITISH COLUMBIA, DEPT MED, DIV NEPHROL, VANCOUVER, BC V6T 1W5, CANADA

来源：

JOURNAL OF UROLOGY | 1995年 / 153卷 / 02期

关键词：

KIDNEY TRANSPLANTATION; TISSUE DONORS; ORGAN TRANSPLANTATION; PEDIATRICS;

D O I：

10.1097/00005392-199502000-00006

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Between July 1987 and July 1993, 762 renal allografts were transplanted into adult recipients at our institution. A total of 83 adults received cadaveric renal transplants from donors aged 5 months to 10 years, while 100 adults who received adult cadaver kidneys during the same period served as a comparison group. Cyclosporine based immunosuppression was used. No difference between the 2 groups was found with respect to recipient age, recipient sex, primary renal disease, HLA matching or the number of recipients with a previous transplant. Actual patient (graft) survivals at 1 and 3 years were 91% (77%) and 86% (68%), respectively, for recipients of pediatric kidneys compared to 99% (92%) and 90% (80%), respectively, for recipients of adult kidneys. Pediatric kidney recipients were more likely to encounter renovascular complications (13% versus 4%, p = 0.023) and more likely to have episodes of acute rejection (p = 0.018). Serum creatinine was equal in the 2 groups at 1 year following transplantation (p = 0.63).

引用

页码：322 / 325

页数：4

共 20 条

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