THE OVALBUMIN FAMILY OF SERPIN PROTEINS

被引：203

作者：

REMOLDODONNELL, E ^{[1
]}

机构：

[1] HARVARD UNIV,SCH MED,DEPT PEDIAT,BOSTON,MA 02115

来源：

FEBS LETTERS | 1993年 / 315卷 / 02期

关键词：

SERPIN; PROTEASE INHIBITOR; PROTEIN FAMILY;

D O I：

10.1016/0014-5793(93)81143-N

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A protein family, the 'Ov-serpins' has been identified by comparing amino acid sequence, protein characteristics and gene organization. The Ov-serpins would not be recognized as a family based on sequence identity alone. This example suggests that combinations of characteristics may need to be examined to identify family groupings within the serpin superfamily.

引用

收藏

页码：105 / 108

页数：4

相关论文

共 27 条

[1] FACULTATIVE POLYPEPTIDE TRANSLOCATION ALLOWS A SINGLE MESSENGER-RNA TO ENCODE THE SECRETED AND CYTOSOLIC FORMS OF PLASMINOGEN ACTIVATORS INHIBITOR-2 [J].

BELIN, D ;

WOHLWEND, A ;

SCHLEUNING, WD ;

KRUITHOF, EKO ;

VASSALLI, JD .

EMBO JOURNAL, 1989, 8 (11) :3287-3294

[2] CLONING AND EXPRESSION OF THE CDNA FOR HUMAN ANTI-THROMBIN-III [J].

BOCK, SC ;

WION, KL ;

VEHAR, GA ;

LAWN, RM .

NUCLEIC ACIDS RESEARCH, 1982, 10 (24) :8113-8125

[3]

BRODBECK RM, 1992, J BIOL CHEM, V267, P294

[4] STRUCTURE AND VARIATION OF HUMAN ALPHA-1-ANTITRYPSIN [J].

CARRELL, RW ;

JEPPSSON, JO ;

LAURELL, CB ;

BRENNAN, SO ;

OWEN, MC ;

VAUGHAN, L ;

BOSWELL, DR .

NATURE, 1982, 298 (5872) :329-334

[5] ANGIOTENSINOGEN IS RELATED TO THE ANTITRYPSIN-ANTITHROMBIN-OVALBUMIN FAMILY [J].

DOOLITTLE, RF .

SCIENCE, 1983, 222 (4622) :417-419

[6]

DUBIN A, 1992, J BIOL CHEM, V267, P6576

[7] PHORBOL ESTER INDUCES THE BIOSYNTHESIS OF GLYCOSYLATED AND NONGLYCOSYLATED PLASMINOGEN-ACTIVATOR INHIBITOR-2 IN HIGH EXCESS OVER UROKINASE-TYPE PLASMINOGEN-ACTIVATOR IN HUMAN U-937 LYMPHOMA-CELLS [J].

GENTON, C ;

KRUITHOF, EKO ;

SCHLEUNING, WD .

JOURNAL OF CELL BIOLOGY, 1987, 104 (03) :705-712

[8] THE OVALBUMIN GENE FAMILY - COMPLETE SEQUENCE AND STRUCTURE OF THE Y-GENE [J].

HEILIG, R ;

MURASKOWSKY, R ;

KLOEPFER, C ;

MANDEL, JL .

NUCLEIC ACIDS RESEARCH, 1982, 10 (14) :4363-4382

[9] ORGANIZATION OF THE HUMAN ALPHA-2-PLASMIN INHIBITOR GENE [J].

HIROSAWA, S ;

NAKAMURA, Y ;

MIURA, O ;

SUMI, Y ;

AOKI, N .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (18) :6836-6840

[10] IMPLICATIONS OF THE 3-DIMENSIONAL STRUCTURE OF ALPHA-1-ANTITRYPSIN FOR STRUCTURE AND FUNCTION OF SERPINS [J].

HUBER, R ;

CARRELL, RW .

BIOCHEMISTRY, 1989, 28 (23) :8951-8966