AMINOACYL NUCLEOSIDES .6. ISOLATION AND PRELIMINARY CHARACTERIZATION OF THREONYLADENINE DERIVATIVES FROM TRANSFER RIBONUCLEIC ACID

被引:65
作者
CHHEDA, GB
HALL, RH
MAGRATH, DI
MOZEJKO, J
SCHWEIZE.MP
STASIUK, L
TAYLOR, PR
机构
[1] Department of Experimental Therapeutics, Roswell Park Memorial Institute, New York State Department of Health, Buffalo
[2] Department of Biochemistry, Australian National University, Canberra
关键词
D O I
10.1021/bi00836a022
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Transfer ribonucleic acid was hydrolyzed by acid under conditions that released the purine residues. Examination of the hydrolysate by means of ion-exchange chromatography on a sulfonic acid resin revealed the presence of a “new” component. This component contains 1 mole of adenine and 1 mole of threonine. It has been detected in the unfractionated transfer ribonucleic acid of yeast (0.28 mole %), Escherichia coli (0.07 mole %), and calf liver (0.19 mole %). © 1969, American Chemical Society. All rights reserved.
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页码:3278 / &
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