CHRONICALLY PERSISTENT INFECTION WITH HUMAN CYTOMEGALO-VIRUS IN HUMAN LYMPHOBLASTS

被引：20

作者：

FURUKAWA, T

YOSHIMURA, N

JEAN, JH

PLOTKIN, SA

机构：

[1] Wistar Institute of Anatomy and Biology, Philadelphia, PA

来源：

JOURNAL OF INFECTIOUS DISEASES | 1979年 / 139卷 / 02期

关键词：

D O I：

10.1093/infdis/139.2.211

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Cells from a line of human lymphocytes originating from a leukemic patient were persistently infected with human cytomegalovirus. Assays of infectious centers and fluorescent antigen staining indicated that 1%-10% of the cells were infected. It appears that persistent infection is due to an equilibrium between the release of virus by infected host cells and the growth of uninfected cells rather than to defective virus or temperature-sensitive mutants. © 1979 by The University of Chicago.

引用

页码：211 / 214

页数：4

共 16 条

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