NEW CHROMOSOME ANOMALY IN ACUTE LYMPHOBLASTIC LEUKEMIA (ALL)

被引：152

作者：

VANDENBERGHE, H ^{[1
]}

DAVID, G ^{[1
]}

BROECKAERTVANORSHOVEN, A ^{[1
]}

LOUWAGIE, A ^{[1
]}

VERWILGHEN, R ^{[1
]}

CASTEELSVANDAELE, M ^{[1
]}

EGGERMONT, E ^{[1
]}

EECKELS, R ^{[1
]}

机构：

[1] CATHOLIC UNIV LEUVEN,DEPT DEV BIOL,DIV HEMATOL & PEDIAT,B-3000 LEUVEN,BELGIUM

来源：

HUMAN GENETICS | 1979年 / 46卷 / 02期

关键词：

D O I：

10.1007/BF00291919

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

A new chromosome anomaly in acute lymphoblastic leukemia (ALL) is reported. Three, possibly four, patients showed an identical karyotype anomaly, characterized by a (4;11)(q13;q22) reciprocal translocation. This anomaly has not so far been found in lymphoproliferative disorders other than ALL. Two of the patients had congenital leukemia, but the anomaly described appears to be more characteristic of ALL than of congenital leukemia, and may help the clinician in establishing the diagnosis of ALL. © 1979 Springer-Verlag.

引用

页码：173 / 180

页数：8

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