LONGITUDINAL-STUDY OF CELLULAR-CHANGES IN EXPERIMENTAL OTITIS-MEDIA

被引：41

作者：

GOYCOOLEA, MV ^{[1
]}

PAPARELLA, MM ^{[1
]}

CARPENTER, AM ^{[1
]}

JUHN, SK ^{[1
]}

机构：

[1] UNIV MINNESOTA, COLL MED, DEPT ANAT, MINNEAPOLIS, MN 55414 USA

来源：

OTOLARYNGOLOGY-HEAD AND NECK SURGERY | 1979年 / 87卷 / 05期

关键词：

D O I：

10.1177/019459987908700524

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

A longitudinal sequential study of otitis media in an experimental animal (cat) using eustachian tube obstruction was done. Fifty animals were used. The continuum of mucoperiosteal changes from one day to six months after obstruction revealed gradual changes that were similar for each animal. Stages were defined, and by using different staining techniques, including immunocytochemistry, an overall middle ear defense system was postulated and documented. Nonspecific as well as specific defense systems including localized immunity, were described. Effusions were studied in a continuum, and their pathogenesis was discussed.

引用

页码：685 / 700

页数：16

共 55 条

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