DOPAMINE RECEPTORS AND SLEEP INDUCTION IN MAN

被引：18

作者：

BASSI, S ^{[1
]}

ALBIZZATI, MG ^{[1
]}

FRATTOLA, L ^{[1
]}

PASSERINI, D ^{[1
]}

TRABUCCHI, M ^{[1
]}

机构：

[1] UNIV BRESCIA,DEPT PHARMACOL THERAPEUT,BRESCIA,ITALY

来源：

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY | 1979年 / 42卷 / 05期

关键词：

D O I：

10.1136/jnnp.42.5.458

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Sleep induction has been studied in humans after the administration of apomorphine, a direct stimulant of the central dopaminergic system. The drug induced sleep and vomiting in healthy volunteers while it had no significant effect on 10 Parkinsonism patients treated for a long period with L-dopa. Apomorphine given to a group of Parkinsonism patients not receiving any specific treatment, and with a lower degree of disease severity, induced vomiting and sleep with a pattern similar to that in healthy subjects. A relationship between the dopaminergic system and sleep induction is suggested.

引用

页码：458 / 460

页数：3

共 14 条

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