SHARED NEUROENDOCRINE PATTERNS OF POSTTRAUMATIC-STRESS-DISORDER AND ALEXITHYMIA

被引:55
作者
HENRY, JP
HAVILAND, MG
CUMMINGS, MA
ANDERSON, DL
NELSON, JC
MACMURRAY, JP
MCGHEE, WH
HUBBARD, RW
机构
[1] LOMA LINDA UNIV,SCH MED,DEPT INTERNAL MED,LOMA LINDA,CA 92354
[2] LOMA LINDA UNIV,SCH MED,DEPT PATHOL,LOMA LINDA,CA 92354
来源
PSYCHOSOMATIC MEDICINE | 1992年 / 54卷 / 04期
关键词
PTSD; ALEXITHYMIA; NOREPINEPHRINE; ACTH; CORTISOL;
D O I
10.1097/00006842-199207000-00003
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
High norepinephrine/cortisol ratios have been shown to be useful indicators of post-traumatic stress disorder (PTSD). Alexithymia can result from overwhelming stress; thus, we hypothesized that sympathetic-adrenal medullary/hypothalamic-pituitary adrenal ratios would be positively associated with alexithymia severity. In the present study, we correlated 3-methoxy-4-hydroxyphenylethylene glycol (MHPG)/adrenocorticotropic hormone (ACTH) and MHPG/cortisol ratios with self-report Toronto Alexithymia Scale (TAS) scores in a group (n = 17) of nondepressed, formerly alcohol-dependent men. The correlations between the respective ratios and TAS scores were 0.515 (p = 0.034) and 0.561 (p = 0.019). We suggest that increasing degrees of alexithymia are accompanied by an increasing separation of these two endocrine systems and then speculate that this dissociation has an anatomical basis in the lateralization of emotions.
引用
收藏
页码:407 / 415
页数:9
相关论文
共 57 条
  • [1] American Psychiatric Association, 1987, DIAGNOSTIC STAT MANU, V3rd
  • [2] ANDERSON DL, UNPUB THYROID STIMUL
  • [3] [Anonymous], [No title captured]
  • [4] ALEXITHYMIA - CONCEPT AND MEASUREMENT
    APFEL, RJ
    SIFNEOS, PE
    [J]. PSYCHOTHERAPY AND PSYCHOSOMATICS, 1979, 32 (1-4) : 180 - 190
  • [5] THE MEASUREMENT OF ALEXITHYMIA - PSYCHOMETRIC PROPERTIES OF THE SCHALLING-SIFNEOS PERSONALITY SCALE
    BAGBY, RM
    TAYLOR, GJ
    RYAN, DP
    [J]. COMPREHENSIVE PSYCHIATRY, 1986, 27 (04) : 287 - 294
  • [6] BAGBY RM, 1991, J CLIN PSYCHOL, V47, P221
  • [7] ALEXITHYMIA - A COMPARATIVE-STUDY OF 3 SELF-REPORT MEASURES
    BAGBY, RM
    TAYLOR, GJ
    ATKINSON, L
    [J]. JOURNAL OF PSYCHOSOMATIC RESEARCH, 1988, 32 (01) : 107 - 116
  • [8] REASSESSING THE VALIDITY AND RELIABILITY OF THE MMPI ALEXITHYMIA SCALE
    BAGBY, RM
    PARKER, JDA
    TAYLOR, GJ
    [J]. JOURNAL OF PERSONALITY ASSESSMENT, 1991, 56 (02) : 238 - 253
  • [9] DYNAMICS OF PLASMA-CATECHOLAMINE AND CORTICOSTERONE CONCENTRATIONS DURING REINFORCED AND EXTINGUISHED OPERANT-BEHAVIOR IN RATS
    DEBOER, SF
    DEBEUN, R
    SLANGEN, JL
    VANDERGUGTEN, J
    [J]. PHYSIOLOGY & BEHAVIOR, 1990, 47 (04) : 691 - 698
  • [10] RESPONSES TO CORTICOTROPIN-RELEASING HORMONE IN THE HYPERCORTISOLISM OF DEPRESSION AND CUSHINGS-DISEASE - PATHOPHYSIOLOGIC AND DIAGNOSTIC IMPLICATIONS
    GOLD, PW
    LORIAUX, DL
    ROY, A
    KLING, MA
    CALABRESE, JR
    KELLNER, CH
    NIEMAN, LK
    POST, RM
    PICKAR, D
    GALLUCCI, W
    AVGERINOS, P
    PAUL, S
    OLDFIELD, EH
    CUTLER, GB
    CHROUSOS, GP
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1986, 314 (21) : 1329 - 1335