FUNCTIONAL-ANALYSIS OF THE LIGAND-BINDING SITE OF EGF-RECEPTOR UTILIZING CHIMERIC CHICKEN HUMAN RECEPTOR MOLECULES

被引：171

作者：

LAX, I ^{[1
]}

BELLOT, F ^{[1
]}

HOWK, R ^{[1
]}

ULLRICH, A ^{[1
]}

GIVOL, D ^{[1
]}

SCHLESSINGER, J ^{[1
]}

机构：

[1] GENENTECH INC,S SAN FRANCISCO,CA 94080

来源：

EMBO JOURNAL | 1989年 / 8卷 / 02期

关键词：

D O I：

10.1002/j.1460-2075.1989.tb03393.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：421 / 427

页数：7

共 20 条

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[2] REQUIREMENT FOR INTRINSIC PROTEIN TYROSINE KINASE IN THE IMMEDIATE AND LATE ACTIONS OF THE EGF RECEPTOR
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[5] A MUTANT EPIDERMAL GROWTH-FACTOR RECEPTOR WITH DEFECTIVE PROTEIN TYROSINE KINASE IS UNABLE TO STIMULATE PROTOONCOGENE EXPRESSION AND DNA-SYNTHESIS
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[6] POINT MUTATION AT THE ATP BINDING-SITE OF EGF RECEPTOR ABOLISHES PROTEIN-TYROSINE KINASE-ACTIVITY AND ALTERS CELLULAR ROUTING
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[7] PROTEIN-TYROSINE KINASES
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[J]. ANNUAL REVIEW OF BIOCHEMISTRY, 1985, 54 : 897 - 930
[8] ANTIBODIES AGAINST A SYNTHETIC PEPTIDE AS A PROBE FOR THE KINASE-ACTIVITY OF THE AVIAN EGF RECEPTOR AND VERBB PROTEIN
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[J]. CELL, 1985, 40 (03) : 619 - 625
[9] CHICKEN EPIDERMAL GROWTH-FACTOR (EGF) RECEPTOR - CDNA CLONING, EXPRESSION IN MOUSE CELLS, AND DIFFERENTIAL BINDING OF EGF AND TRANSFORMING GROWTH FACTOR-ALPHA
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[J]. MOLECULAR AND CELLULAR BIOLOGY, 1988, 8 (05) : 1970 - 1978
[10] LOCALIZATION OF A MAJOR RECEPTOR-BINDING DOMAIN FOR EPIDERMAL GROWTH-FACTOR BY AFFINITY LABELING
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GIVOL, D
[J]. MOLECULAR AND CELLULAR BIOLOGY, 1988, 8 (04) : 1831 - 1834

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