HEMODYNAMICS OF THE CENTRAL-NERVOUS-SYSTEM ARTERIOVENOUS MALFORMATION NIDUS DURING PARTICULATE EMBOLIZATION - A COMPUTER-MODEL

被引:19
作者
HECHT, ST
HORTON, JA
KERBER, CW
机构
[1] UNIV CALIF SAN DIEGO,MED CTR,DEPT RADIOL,LA JOLLA,CA 92093
[2] UNIV CALIF SAN DIEGO,MED CTR,DEPT NEUROSURG,LA JOLLA,CA 92093
[3] UNIV PITTSBURGH,DEPT RADIOL,PITTSBURGH,PA 15260
[4] UNIV PITTSBURGH,DEPT NEUROSURG,PITTSBURGH,PA 15260
关键词
ARTERIOVENOUS MALFORMATIONS; NIDUS; HEMODYNAMICS;
D O I
10.1007/BF00593337
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
We have modelled the hemodynamics of the nidus of the central nervous system (CNS) arteriovenous malformation (AVM) during the process of particulate embolization. The model accurately reproduces the visually apparent incremental slowing observed during such embolization of CNS AVMs. The model is simple and proposes that the nidus is composed of many identical microchannels. As the microchannels are occluded by particles at a constant rate, the rate of change of flow reduction with each bolus of emboli constantly increases exponentially. A rapid reduction in apparent flow rate occurs immediately prior to complete occlusion. With a more accurate understanding of the workings of the nidus of CNS AVMs we can increase the safety of therapeutic particulate embolization.
引用
收藏
页码:62 / 64
页数:3
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