ERYTHROPOIETIN AND SPONTANEOUS PLATELET-AGGREGATION IN HEMODIALYSIS-PATIENTS

被引：60

作者：

TAYLOR, JE ^{[1
]}

HENDERSON, IS ^{[1
]}

STEWART, WK ^{[1
]}

BELCH, JJF ^{[1
]}

机构：

[1] UNIV DUNDEE, NINEWELLS HOSP & MED SCH, DEPT MED, DUNDEE DD1 9SY, SCOTLAND

来源：

LANCET | 1991年 / 338卷 / 8779期

关键词：

D O I：

10.1016/0140-6736(91)92239-X

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Erythropoietin significantly, reversibly, and reproducibly increased in-vitro whole-blood spontaneous platelet aggregation in 15 patients on haemodialysis. During erythropoietin treatment, spontaneous platelet aggregation was significantly higher in these subjects than in non-uraemic controls; concomitant treatment with 300 mg aspirin daily reversed platelet hyperaggregability. Erythropoietin may promote thrombosis by an effect on platelet function.

引用

页码：1361 / 1362

页数：2

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