CHLORAMPHENICOL - EFFECTS ON MOUSE MYELOMA CELLS IN TISSUE CULTURE

被引：20

作者：

HARTMAN, BK

PETTENGILL, OS

SORENSON, GD

机构：

[1] Department of Pathology, Washington University, School of Medicine, St. Louis

来源：

SCIENCE | 1969年 / 165卷 / 3890期

关键词：

D O I：

10.1126/science.165.3890.297

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Within 36 hours of being administered, chloramphenicol (50 micrograms per milliliter) inhibits by 50 percent the rate of protein synthesis in mouse myeloma cells grown in suspension culture. Although there is a decrease in the amount of globulin synthesized, the rate of synthesis per cell is unchanged; the observed decrease is traced to the inhibition of cell proliferation caused by chloramphenicol.

引用

页码：297 / +

页数：1

共 13 条

[1] STUDIES ON ANTIBODY PRODUCTION .8. INHIBITORY EFFECT OF CHLORAMPHENICOL ON SYNTHESIS OF ANTIBODY IN TISSUE CULTURE [J].