ALTERNATIVE TRANSCRIPTS OF THE RAT AND HUMAN DOPAMINE-D3 RECEPTOR

被引：55

作者：

SNYDER, LA

ROBERTS, JL

SEALFON, SC

机构：

[1] CUNY GRAD SCH & UNIV CTR,CTR GRAD,PH D PROGRAM BIOL,33 W 42 ST,NEW YORK,NY 10036

[2] CUNY MT SINAI SCH MED,FISHBERG RES CTR NEUROBIOL,DEPT NEUROBIOL,NEW YORK,NY 10029

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1991年 / 180卷 / 02期

关键词：

D O I：

10.1016/S0006-291X(05)81169-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A cDNA for the rat dopamine D3 receptor containing a 113 bp deletion has been isolated. The segment deleted, encompassing the first extracellular loop and third transmembrane domain, alters the reading frame, introducing 19 amino acids not found in the full length receptor followed by a premature stop codon. This novel mRNA encodes a 109 amino acid protein containing two putative tranmembrane domains. A similar variant cDNA for the human D3 receptor has also been identified. © 1991 Academic Press, Inc.

引用

页码：1031 / 1035

页数：5

共 18 条

[1] DOPAMINE D2-RECEPTOR MESSENGER-RNA IS DIFFERENTIALLY REGULATED BY DOPAMINERGIC AGENTS IN RAT ANTERIOR AND NEUROINTERMEDIATE PITUITARY
AUTELITANO, DJ
SNYDER, L
SEALFON, SC
ROBERTS, JL
[J]. MOLECULAR AND CELLULAR ENDOCRINOLOGY, 1989, 67 (01) : 101 - 105
[2] PURIFICATION OF BIOLOGICALLY-ACTIVE GLOBIN MESSENGER-RNA BY CHROMATOGRAPHY ON OLIGOTHYMIDYLIC-ACID-CELLULOSE
AVIV, H
LEDER, P
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1972, 69 (06) : 1408 - &
[3] GAMMA-AMINOBUTYRIC ACIDA RECEPTOR HETEROGENEITY IS INCREASED BY ALTERNATIVE SPLICING OF A NOVEL BETA-SUBUNIT GENE TRANSCRIPT
BATESON, AN
LASHAM, A
DARLISON, MG
[J]. JOURNAL OF NEUROCHEMISTRY, 1991, 56 (04) : 1437 - 1440
[4] A METHOD FOR ISOLATION OF INTACT, TRANSLATIONALLY ACTIVE RIBONUCLEIC-ACID
CATHALA, G
SAVOURET, JF
MENDEZ, B
WEST, BL
KARIN, M
MARTIAL, JA
BAXTER, JD
[J]. DNA-A JOURNAL OF MOLECULAR & CELLULAR BIOLOGY, 1983, 2 (04): : 329 - 335
[5] ANALYSIS OF THE STRUCTURE AND EXPRESSION OF THE HUMAN DOPAMINE-D2A RECEPTOR GENE
GANDELMAN, KY
HARMON, S
TODD, RD
OMALLEY, KL
[J]. JOURNAL OF NEUROCHEMISTRY, 1991, 56 (03) : 1024 - 1029
[6] SHORTER VARIANTS OF THE D3 DOPAMINE RECEPTOR PRODUCED THROUGH VARIOUS PATTERNS OF ALTERNATIVE SPLICING
GIROS, B
MARTRES, MP
PILON, C
SOKOLOFF, P
SCHWARTZ, JC
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1991, 176 (03) : 1584 - 1592
[7] GIROS B, 1990, CR ACAD SCI III-VIE, V311, P501
[8] LUTEINIZING-HORMONE RELEASE FROM DISSOCIATED PITUITARY-CELLS BY DIMERIZATION OF OCCUPIED LHRH RECEPTORS
GREGORY, H
TAYLOR, CL
HOPKINS, CR
[J]. NATURE, 1982, 300 (5889) : 269 - 271
[9] Innis M., 1990, PCR PROTOCOLS GUIDE, P3
[10] Kahn C R, 1981, Recent Prog Horm Res, V37, P477

← 1 2 →