ENANTIOSELECTIVE SYNTHESIS OF 2,2-DIALKYLTETRAHYDROPYRAN-3-ONES VIA THE ASYMMETRIC MICHAEL ADDITION-REACTION USING CHIRAL IMINES

被引：10

作者：

DESMAELE, D

PAIN, G

DANGELO, J

机构：

[1] Laboratoire de Chimie Organique, Faculté de Pharmacie, 92296 Châtenay- Malabry, 5, rue J.- B. Clément

来源：

TETRAHEDRON-ASYMMETRY | 1992年 / 3卷 / 07期

关键词：

CHIRAL IMINE; ASYMMETRIC MICHAEL ADDITION REACTION; CHIRAL 2,2-DIALKYLTETRAHYDROPYRAN-3-ONES; CIRCULAR DICHROISM;

D O I：

10.1016/S0957-4166(00)82185-0

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Addition of chiral imine 8 derived from 2-methyltetrahydropyran-3-one 7 and R-(+)-1-phenylethylamine, to methyl acrylate led to adduct (S)-9 with a good yield and an excellent stereoselectivity.

引用

页码：863 / 866

页数：4

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